Direct flights
from Chicago (ORD)
to Des Moines (DSM)

Weekly schedule for flights between Chicago O'Hare Intl (Chicago, United States) and Des Moines Intl (Des Moines, United States) operated by 1 airlines.
49 weekly flights operate on this route flying 299mi in 1h37min.
Expect $435 in average for a one-way ticket with the cheapest option at $179.